Most potential new drugs fail when they're tested in people. These failures are not only a major disappointment, they sharply drive up the cost of developing new drugs.

A major reason for these failures is that most new drugs are first tested out in mice, rats or other animals. Often those animal studies show great promise.

But mice aren't simply furry little people, so these studies often lead science astray. Some scientists are now rethinking animal studies to make them more effective for human health.

Around the U.S., a worsening heroin epidemic has more and more cities turning to the anti-overdose drug naloxone to reduce deaths from abuse. Also known as Narcan, the medication blocks the effects of opioids and reverses the respiratory depression that occurs during an overdose.

Three Floridians are looking at stretches in prison after pleading guilty to a conspiracy to acquire and distribute the illegal synthetic drug known as "spice."

All three are from the Tampa area. Pleading guilty to a pair of federal drug conspiracy charges were 28-year-old Ahmed Yehia Khalifa and 25-year-old Ahmed Maher Elhelw. They face up to 20 years in prison on each charge and have agreed to forfeit more than $472,000 in assets.

Some Workers Exempt From Drug Tests, But Fight Drags On

Jul 9, 2014
Florida House of Representatives

  Gov. Rick Scott has capitulated in his crusade to require all state workers to submit to suspicionless drug tests, giving up on about half of the state's classes of workers in a drawn-out legal battle that could end up before the U.S. Supreme Court.

Synthetic Drug Sends 28 to Hospital

Jun 2, 2014

Two synthetic marijuana products -- identified as "Scooby Snax" and "Purple Flake" -- have sent more than two dozen people to the hospital in Gainesville. Health and police department officials are unsure as to whether or not the tainted products, commonly called "spice," are being sold in other areas since they are illegal and hard to track.

But both law enforcement and health workers may want to be on the lookout. The drugs are apparently tainted and “highly toxic,” according to Alachua County Health Department Director Paul Myers.

As part of baseball star Alex Rodriguez's lawsuit against Major League Baseball and the players union, a federal judge ordered the release of an important opinion from the arbitrator who found the league was justified in suspending Rodriguez for the 2014 season and postseason.

Scott McIntyre / AP Photo/Naples Daily News

A month after pleading guilty to cocaine-possession charges, Republican Rep. Trey Radel of Florida refused to resign Thursday, saying he wants to "rebuild the trust" of voters.

At a news conference held the same day he left a drug and alcohol rehabilitation center, the 37-year-old freshman told reporters at his Cape Coral office that he will cooperate with congressional investigators who are looking into his conduct.

Republican Rep. Henry "Trey" Radel of Florida pleaded guilty Wednesday morning to misdemeanor cocaine possession.

That plea in a Washington, D.C., court comes one day after word that Radel had been charged with buying $260 worth of the drug from an undercover Drug Enforcement Administration agent.

Just when you wrapped your brain around bath salts, the Drug Enforcement Administration is warning parents and schools about three new synthetic drugs:

1) "Smiles" is a hallucinogen whose effects are not immediately felt, increasing the risk of overdose. It can be taken as small tables, on blotter paper, or in powder form, often mixed with something else--chocolate, for instance. Side effects include loss of control, panic, heart palpitations and memory loss.